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Spectral CT IDs heart plaque better than conventional
Researchers can for the first time visualize coronary artery plaques vulnerable to rupture using spectral CT, an innovation that will lead to better and earlier diagnosis of cardiovascular disease, according to researchers.
Researchers can for the first time visualize coronary artery plaques vulnerable to rupture using spectral CT, an innovation that will lead to better and earlier diagnosis of cardiovascular disease, according to researchers.
Ruptured atherosclerotic plaques are the cause of nearly 70% of heart attacks. High-density lipoproteins (HDL) gravitate to plaques vulnerable to rupture and remove them from the arterial wall. Researchers from Mount Sinai in New York inserted tiny gold particles into HDL and injected mice with them. Using a spectral CT scanner from Philips Medical Systems, the researchers were able to see the gold particles as the HDL targeted microphages, thus illuminating the location of the vulnerable plaques.
Conventional CT doesn’t provide enough contrast to differentiate types and density of tissue. Spectral CT shows the effect of gold particles while also distinguishing calcium deposits and contrast agents. Together, this information is used to identify stenoses, thus helping define both the severity of atherosclerosis and heart attack risk.
Study Reaffirms Low Risk for csPCa with Biopsy Omission After Negative Prostate MRI
December 19th 2024In a new study involving nearly 600 biopsy-naïve men, researchers found that only 4 percent of those with negative prostate MRI had clinically significant prostate cancer after three years of active monitoring.
Study Examines Impact of Deep Learning on Fast MRI Protocols for Knee Pain
December 17th 2024Ten-minute and five-minute knee MRI exams with compressed sequences facilitated by deep learning offered nearly equivalent sensitivity and specificity as an 18-minute conventional MRI knee exam, according to research presented recently at the RSNA conference.
Can Radiomics Bolster Low-Dose CT Prognostic Assessment for High-Risk Lung Adenocarcinoma?
December 16th 2024A CT-based radiomic model offered over 10 percent higher specificity and positive predictive value for high-risk lung adenocarcinoma in comparison to a radiographic model, according to external validation testing in a recent study.
