Whole-body MRI and PET/CT can miss many metastases
German researchers were stunned to discover that whole-body staging of patients with recently diagnosed malignancies using either MRI or PET/CT could miss a substantial number of metastatic lesions. They released their data at the 2007 RSNA meeting.
German researchers were stunned to discover that whole-body staging of patients with recently diagnosed malignancies using either MRI or PET/CT could miss a substantial number of metastatic lesions. They released their data at the 2007 RSNA meeting.
Dr. Florian Vogt and colleagues at the University Hospital of Essen enrolled 60 consecutive patients who underwent whole-body 1.5T MRI and whole-body FDG-PET/CT for staging of regional and distant melanoma metastases after primary tumor resection. Fifty-six patients completed the mean follow-up of 748 days. The researchers found that a significant number of patients initially staged as negative eventually proved to have undetected metastatic disease.
Another research group from Essen led by Dr. Gerald Antoch also evaluated the accuracy of whole-body FDG-PET/CT and whole-body MRI for staging and detection of bone metastases in 55 patients with melanoma and 54 with non-small cell lung cancer. The investigators found that, despite their accuracy for detection and staging, both tests yielded a significant rate of false negatives.
New MRI Research Explores Links Between Waist-to-Hip Ratio and Memory in Aging
March 13th 2025Researchers found that a higher waist-to-hip ratio in midlife was associated with higher mean diffusivity in 26 percent of total white matter tracts in the cingulum as well as the superior and inferior longitudinal fasciculus.
Meta-Analysis Shows No Difference Between bpMRI and mpMRI in Ruling Out csPCa
March 6th 2025In an 18-study meta-analysis involving over 4,600 patients, researchers found that bpMRI and mpMRI had equivalent pooled negative predictive value (NPV) of 92 percent for clinically significant prostate cancer (csPCa).
