T1-weighted MRI identifies signs of multiple sclerosis
Long-standing suspicions about noncontrast T1-weighted MRI's usefulness as a biomarker for multiple sclerosis have been confirmed in a study showing that hyperintense plaques revealed with the technique are associated with brain atrophy, disability, and an advancing course for the disease.
Long-standing suspicions about noncontrast T1-weighted MRI's usefulness as a biomarker for multiple sclerosis have been confirmed in a study showing that hyperintense plaques revealed with the technique are associated with brain atrophy, disability, and an advancing course for the disease.
Dr. Vallabh Janardhan and colleagues at Brigham and Women's Hospital in Boston and State University of New York at Buffalo retrospectively reviewed data from 145 MS patients who underwent unenhanced T1-weighted MRI from July 1995 to June 1999. Ninety-two patients had relapsing-remitting MS, and 49 were diagnosed with secondary-progressive MS. The disease type was unknown in four cases. The investigators found a significant correlation between hyperintense lesions, detected with noncontrast T1-weighted MRI, and secondary-progressive MS (Radiology 2007;244:823-831).
The Reading Room Podcast: Current Perspectives on the Updated Appropriate Use Criteria for Brain PET
March 18th 2025In a new podcast, Satoshi Minoshima, M.D., Ph.D., and James Williams, Ph.D., share their insights on the recently updated appropriate use criteria for amyloid PET and tau PET in patients with mild cognitive impairment.
Study with CT Data Suggests Women with PE Have More Than Triple the One-Year Mortality Rate than Men
April 3rd 2025After a multivariable assessment including age and comorbidities, women with pulmonary embolism (PE) had a 48 percent higher risk of one-year mortality than men with PE, according to a new study involving over 33,000 patients.
