• AI
  • Molecular Imaging
  • CT
  • X-Ray
  • Ultrasound
  • MRI
  • Facility Management
  • Mammography

SPECT + Deep Learning = Accurate Major Cardiac Event Prediction

Article

Using advanced artificial intelligence can give patients a personalized assessment of their risk for significant events, such as heart attack or death.

Deep learning does a better job in predicting which patients will experience major adverse cardiac events than the current standard imaging protocols used to make these determinations, according to new research.

In a poster presented during the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting, researchers from Cedars-Sinai Medical Center in Los Angeles created a novel deep learning algorithm that can give patients a personalized assessment of their annualized risk for these types of events, such as heart attack of death.

For more SNMMI 2021 Annual Meeting coverage, click here.

“These findings show that artificial intelligence could be incorporated in standard clinical workstations to assist physicians in accurate and fast risk assessment of patients undergoing SPECT MPI scans,” said Ananya Singh, MS, a research software engineer in the Slomka Lab at Cedars-Sinai. “This work signifies the potential advantage of incorporating artificial intelligence techniques in standard imaging protocols to assist readers with risk stratification.”

Prediction performance of DL compared to quantitative measures and Kaplan-Meier curves for quartiles of DL.

Credit: Image created by Singh et al., Cedars-Sinai Medical Center, Los Angeles, CA.

Prediction performance of DL compared to quantitative measures and Kaplan-Meier curves for quartiles of DL.

Credit: Image created by Singh et al., Cedars-Sinai Medical Center, Los Angeles, CA.

To build their deep learning network, the team pulled data from 20,401 patients included in the largest available multi-center SPECT dataset – REgistry of Fast myocardial perfusion Imaging in NExt generation SPECT (REFINE SPECT). All patients had undergone SPECT MPI. The team used their network to score each patient on their individual likelihood to have a major adverse cardiac event during the average follow-up period of 4.7 years.

According to their analysis, the network was able to pinpoint the areas of the heart that were associated with an elevated risk of these events and return a risk score in less than 1 second. They determined that the patients with the highest deep learning scores had a 9.7-percent annual major cardiac event rate – a 10.2-fold increased risk over patients with the lowest scores.

For more coverage based on industry expert insights and research, subscribe to the Diagnostic Imaging e-Newsletter here.

Recent Videos
Radiology Study Finds Increasing Rates of Non-Physician Practitioner Image Interpretation in Office Settings
Emerging Research at SNMMI Examines 18F-flotufolastat in Managing Primary and Recurrent Prostate Cancer
Could Pluvicto Have a Role in Taxane-Naïve mCRPC?: An Interview with Oliver Sartor, MD
New SNMMI President Cathy Cutler, PhD, Discusses Current Challenges and Goals for Nuclear Medicine
Does Initial CCTA Provide the Best Assessment of Stable Chest Pain?
Nina Kottler, MD, MS
Practical Insights on CT and MRI Neuroimaging and Reporting for Stroke Patients
Related Content
© 2024 MJH Life Sciences

All rights reserved.