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Scorpion venom helps treat brain tumors
A new method of delivering a dose of radioactive iodine by using a manufactured version of scorpion venom as a carrier targets gliomas without affecting neighboring tissue or body organs.
The first trial in human patients showed the approach to be safe. A larger phase II trial is under way to assess the effectiveness of multiple doses. Dr. Adam N. Mamelak, a neurosurgeon at Cedars-Sinai Medical Center in Los Angeles, led the phase I trial and is first author of an article in the August Journal of Clinical Oncology.
The key ingredient is TM-601, a synthetic version of a peptide found in the venom of the giant yellow Israeli scorpion (Leiurus quinquestriatus). TM-601 can break through the blood-brain barrier, binding to glioma cells and impeding their growth. If further studies confirm TM-601's properties, it could be used in tandem with standard treatments and allow for reduced doses, the researchers said.
FDA Grants Expanded 510(k) Clearance for Xenoview 3T MRI Chest Coil in GE HealthCare MRI Platforms
November 21st 2024Utilized in conjunction with hyperpolarized Xenon-129 for the assessment of lung ventilation, the chest coil can now be employed in the Signa Premier and Discovery MR750 3T MRI systems.
New Study Examines Agreement Between Radiologists and Referring Clinicians on Follow-Up Imaging
November 18th 2024Agreement on follow-up imaging was 41 percent more likely with recommendations by thoracic radiologists and 36 percent less likely on recommendations for follow-up nuclear imaging, according to new research.
