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PIB-PET opens diagnostic front in Alzheimer's disease
Australian researchers using PET imaging with Pittsburgh Compound B found a link between the progressive accumulation of beta-amyloid plaque in the brain and mild cognitive impairment and Alzheimer's disease. Findings could pertain to anti-amyloid drugs now in clinical trials.
Australian researchers using PET imaging with Pittsburgh Compound B found a link between the progressive accumulation of beta-amyloid plaque in the brain and mild cognitive impairment and Alzheimer's disease. Findings could pertain to anti-amyloid drugs now in clinical trials.
Dr. Christopher C. Rowe, director of nuclear medicine at the Austin Hospital's Centre for PET in Melbourne, and colleagues evaluated 44 Alzheimer's patients, 44 patients with mild cognitive impairment, and 34 healthy controls. The trial correlated results from psychometric memory tests and PIB standard uptake values in the frontal, posterior cingulate, parietal, lateral temporal, and occipital brain regions. Researchers found cortical PIB binding in all Alzheimer's patients, 60% of subjects with measurable cognitive deficits, and 20% of healthy volunteers. Findings were presented at the 2007 SNM meeting.
Can Generative AI Facilitate Simulated Contrast Enhancement for Prostate MRI?
January 14th 2025Deep learning synthesis of contrast-enhanced MRI from non-contrast prostate MRI sequences provided an average multiscale structural similarity index of 70 percent with actual contrast-enhanced prostate MRI in external validation testing from newly published research.
Can MRI Have an Impact with Fertility-Sparing Treatments for Endometrial and Cervical Cancers?
January 9th 2025In a literature review that includes insights from recently issued guidelines from multiple European medical societies, researchers discuss the role of magnetic resonance imaging (MRI) in facilitating appropriate patient selection for fertility-sparing treatments to address early-stage endometrial and cervical cancer.
