Magnetic resonance imaging’s accuracy in detecting cancer in the lymph nodes of newly diagnosed breast cancer patients is nothing to sniff at – 80 percent with diffusion-weighted MRI and 85 percent with axial T1-weighted MRI, Canadian researchers have reported. But it’s not quite high enough to skip a lymph node dissection, according to a study published online Dec. 5 in the journal Radiology.
Magnetic resonance imaging’s accuracy in detecting cancer in the lymph nodes of newly diagnosed breast cancer patients is nothing to sniff at – 80 percent with diffusion-weighted MRI and 85 percent with axial T1-weighted MRI, Canadian researchers have reported. But it’s not quite high enough to skip a lymph node dissection, according to a study published online Dec. 5 in the journal Radiology.
University of Toronto researchers chose 61 women (average age 53) with invasive breast cancer to undergo preoperative breast MRI. Axial T1-weighted MRI without fat saturation and diffusion-weighted (DW) MR images were analyzed by two experienced radiologists uninformed of the pathology findings.
They found the sensitivity, specificity, and accuracy to be 88 percent, 82 percent, and 85 percent, respectively, for axial T1-weighted MR imaging and 84 percent, 77 percent, and 80 percent for diffusion-weighted (DW) imaging. Apparent diffusion coefficients (ADCs) were significantly lower in the malignant group.
The team concluded that unenhanced MRI techniques showed high accuracy in the preoperative evaluation of patients with invasive breast cancer, and that, while the results indicated reliable and reproducible assessment with DW imaging, “it is unlikely to be useful in clinical practice.”
The Reading Room Podcast: Current Perspectives on the Updated Appropriate Use Criteria for Brain PET
March 18th 2025In a new podcast, Satoshi Minoshima, M.D., Ph.D., and James Williams, Ph.D., share their insights on the recently updated appropriate use criteria for amyloid PET and tau PET in patients with mild cognitive impairment.
Study with CT Data Suggests Women with PE Have More Than Triple the One-Year Mortality Rate than Men
April 3rd 2025After a multivariable assessment including age and comorbidities, women with pulmonary embolism (PE) had a 48 percent higher risk of one-year mortality than men with PE, according to a new study involving over 33,000 patients.