RI should be included among the World Health Organization's options for diagnosing sporadic Creutzfeldt-Jakob disease, which is associated with exposure to mad cow disease, according to Dr. Henriette Tschampa and colleagues at the Clinical University of Bonn, Germany.
MRI should be included among the World Health Organization's options for diagnosing sporadic Creutzfeldt-Jakob disease, which is associated with exposure to mad cow disease, according to Dr. Henriette Tschampa and colleagues at the Clinical University of Bonn, Germany.
The researchers enrolled 193 consecutive patients suspected of having the condition. In 442 scans, MR's sensitivity and specificity were nearly 70% and 85%, respectively, in patients with a clinical or postmortem sCJD diagnosis. Sensitivity and specificity for EEG and 14-3-3 protein analysis were 32% and 94%, and 91% and 44%, respectively, they reported at the RSNA meeting. Even though interpretation of MR scans may require some effort, the modality provides useful information that could narrow down an sCJD diagnosis.
Is MRI Contrast Enhancement Necessary for Long-Term Monitoring of Diffuse Glioma?
March 4th 2025In a comparison of contrast-enhanced T1-weighted (CET1w) MRI (and T2-weighted MRI/FLAIR imaging, researchers found that only three out of 82 cases of glioma progression were solely detected with CET1w MRI.