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F-18 PET shows early diabetes risk
Prior to the onset of diabetes, the number of pancreatic beta cells declines. New preclinical research shows that these beta cells can be quantified noninvasively with a targeted molecular probe, thereby acting as an early marker for disease risk.
Prior to the onset of diabetes, the number of pancreatic beta cells declines. New preclinical research shows that these beta cells can be quantified noninvasively with a targeted molecular probe, thereby acting as an early marker for disease risk.
Earlier research used a carbon-based probe to target the vesicular monoamine transporter-2 (VMAT2), which is expressed by the beta cells of the pancreas. In order to generate a more widely applicable probe, Dr. Mei-Ping Kung and colleagues at the University of Pennsylvania developed F-18 FP-DTBZ. They found that the F-18 ligand bound to VMAT2 targets, which were decreased in rats with diabetes. The research got a boost when it won the 2007 SNM "Small Animal Image of the Year" award.
Study Reaffirms Low Risk for csPCa with Biopsy Omission After Negative Prostate MRI
December 19th 2024In a new study involving nearly 600 biopsy-naïve men, researchers found that only 4 percent of those with negative prostate MRI had clinically significant prostate cancer after three years of active monitoring.
Study Examines Impact of Deep Learning on Fast MRI Protocols for Knee Pain
December 17th 2024Ten-minute and five-minute knee MRI exams with compressed sequences facilitated by deep learning offered nearly equivalent sensitivity and specificity as an 18-minute conventional MRI knee exam, according to research presented recently at the RSNA conference.
Can Radiomics Bolster Low-Dose CT Prognostic Assessment for High-Risk Lung Adenocarcinoma?
December 16th 2024A CT-based radiomic model offered over 10 percent higher specificity and positive predictive value for high-risk lung adenocarcinoma in comparison to a radiographic model, according to external validation testing in a recent study.
