Cytogen’s Quadramet wins FDA nod

Article

Monoclonal antibody developer Cytogen of Princeton, NJ, has received the Food and Drug Administration's go-ahead to market its Quadramet cancer therapy agent for relieving pain in patients whose cancer has spread to the bone. Quadramet is indicated in

Monoclonal antibody developer Cytogen of Princeton, NJ, has received the Food and Drug Administration's go-ahead to market its Quadramet cancer therapy agent for relieving pain in patients whose cancer has spread to the bone. Quadramet is indicated in patients with osteoblastic metastatic bone lesions, which can be caused by prostate, bone, or breast cancer.

Quadramet will be marketed in the U.S., Canada, and Latin America by Du Pont Merck Radiopharmaceuticals, with shipments scheduled to begin this quarter. The news of the FDA's action caused Cytogen's stock to surge 56, or 11%, to end at $5.81 on March 31, the day the news was announced.

In other Cytogen news, the company said that it has begun phase I clinical trials investigating the use of Quadramet for treating patients with refractory rheumatoid arthritis. The study will be conducted at the University of Iowa and will enroll about 30 patients.

Another Cytogen technology, prostate specific membrane antigen (PSMA), has shown promise in preliminary research as a possible vaccine to fight prostate cancer. Cytogen has licensed PSMA technology to a company called Prostagen, which is researching the use of immunotherapy for advanced prostate cancer.

Recent Videos
Improving Access to Nuclear Imaging: An Interview with SNMMI President Jean-Luc C. Urbain, MD, PhD
SNMMI: 18F-Piflufolastat PSMA PET/CT Offers High PPV for Local PCa Recurrence Regardless of PSA Level
SNMMI: NIH Researcher Discusses Potential of 18F-Fluciclovine for Multiple Myeloma Detection
SNMMI: What Tau PET Findings May Reveal About Modifiable Factors for Alzheimer’s Disease
Emerging Insights on the Use of FES PET for Women with Lobular Breast Cancer
Can Generative AI Reinvent Radiology Reporting?: An Interview with Samir Abboud, MD
Mammography Study Reveals Over Sixfold Higher Risk of Advanced Cancer Presentation with Symptom-Detected Cancers
Combining Advances in Computed Tomography Angiography with AI to Enhance Preventive Care
Study: MRI-Based AI Enhances Detection of Seminal Vesicle Invasion in Prostate Cancer
What New Research Reveals About the Impact of AI and DBT Screening: An Interview with Manisha Bahl, MD
Related Content
© 2025 MJH Life Sciences

All rights reserved.