Cytogen chooses Berlex for Quadramet

Article

After months of searching for a new partner to market its bone cancer therapeutic agent Quadramet, radiopharmaceutical firm Cytogen of Princeton, NJ, announced Oct. 29 that it had signed an exclusive license agreement with Berlex Laboratories for the

After months of searching for a new partner to market its bone cancer therapeutic agent Quadramet, radiopharmaceutical firm Cytogen of Princeton, NJ, announced Oct. 29 that it had signed an exclusive license agreement with Berlex Laboratories for the manufacture and sale of the product. The deal covers marketing and sales in North and South America, and the two companies are in the process of securing a long-term supply agreement with Du Pont Pharmaceutical of North Billerica, MA, Cytogen’s former marketing partner and current contract manufacturer of Quadramet.

Berlex will pay Cytogen $8 million when the supply agreement with Du Pont is finalized. Cytogen will pay half of the money to Du Pont to establish a five-year manufacturing deal. Berlex will also pay royalties to Cytogen on net sales of Quadramet, as well as milestone payments for achieving predetermined sales levels. The Montville, NJ, company expects to begin marketing Quadramet in January 1999. Cytogen plans to conclude phase IV post-approval studies required by the Food and Drug Administration in its clearance of Quadramet.

The Berlex deal closes an interim agreement between Cytogen and Du Pont, in which Du Pont agreed to identify marketing partner candidates for Cytogen (SCAN 10/28/98).

Recent Videos
New Mammography Studies Assess Image-Based AI Risk Models and Breast Arterial Calcification Detection
Can Deep Learning Provide a CT-Less Alternative for Attenuation Compensation with SPECT MPI?
Employing AI in Detecting Subdural Hematomas on Head CTs: An Interview with Jeremy Heit, MD, PhD
Pertinent Insights into the Imaging of Patients with Marfan Syndrome
What New Brain MRI Research Reveals About Cannabis Use and Working Memory Tasks
Current and Emerging Legislative Priorities for Radiology in 2025
How Will the New FDA Guidance Affect AI Software in Radiology?: An Interview with Nina Kottler, MD, Part 2
A Closer Look at the New Appropriate Use Criteria for Brain PET: An Interview with Phillip Kuo, MD, Part 2
How Will the New FDA Guidance Affect AI Software in Radiology?: An Interview with Nina Kottler, MD, Part 1
A Closer Look at the New Appropriate Use Criteria for Brain PET: An Interview with Phillip Kuo, MD, Part 1
Related Content
© 2025 MJH Life Sciences

All rights reserved.