MR perfusion imaging, along with intracoronary pressure data, may help identify hemodynamically relevant coronary artery diseases, according to a study presented this week at the North American Society for Cardiac Imaging meeting in Amelia Island, FL.
MR perfusion imaging, along with intracoronary pressure data, may help identify hemodynamically relevant coronary artery diseases, according to a study presented this week at the North American Society for Cardiac Imaging meeting in Amelia Island, FL.
Dr. Armin M. Huber and colleagues from the Klinikum Grosshadern and Klinikum Innenstadt in Munich found that semiquantitative MR perfusion parameters with results from intracoronary pressure-derived fractional flow reserve correctly assessed the hemodynamic relevance of known coronary artery lesions.
Twenty-one patients underwent coronary MR angiography with intracoronary pressure wire examination for determination of fractional flow reserve in 23 stenotic lesions. SI curves of the first-pass MR perfusion imaging (SR-turboFLASH) of the myocardium were analyzed at rest and under adenosine-induced hyperemia.
Researchers determined time-to-peak, maximum signal intensity, and upslope values using a 16-segment model. They divided lesions into three groups:
A total of 336 perfusion areas were evaluated. Time-to-peak and upslope at rest values were not significantly different among the three groups. Stress upslope measurements of normal coronary arteries and severe coronary stenoses, however, were significantly different.
The ratio for upslope at stress and rest was 3.4 (2.0-6.3) for normal coronary arteries and 1.7 (1.2-1.7) and 1.1 (1.0-1.3) for intermediate and severe coronary lesions (p
Time-to-peak and upslope at rest measurements were not able to discriminate between normal and severely stenosed coronary arteries, Huber said. Measurements for upslope under stress and the ratio between upslope under stress and upslope at rest were significantly different between normal and significantly functionally diseased coronary arteries.
"The use of these MRI parameters may therefore improve the sensitivity and specificity of noninvasive identification of hemodynamically relevant CAD," he said.
Can Generative AI Facilitate Simulated Contrast Enhancement for Prostate MRI?
January 14th 2025Deep learning synthesis of contrast-enhanced MRI from non-contrast prostate MRI sequences provided an average multiscale structural similarity index of 70 percent with actual contrast-enhanced prostate MRI in external validation testing from newly published research.
Can MRI Have an Impact with Fertility-Sparing Treatments for Endometrial and Cervical Cancers?
January 9th 2025In a literature review that includes insights from recently issued guidelines from multiple European medical societies, researchers discuss the role of magnetic resonance imaging (MRI) in facilitating appropriate patient selection for fertility-sparing treatments to address early-stage endometrial and cervical cancer.
Surveillance Breast MRI Associated with Lower Risks of Advanced Second Breast Cancers
January 8th 2025After propensity score matching in a study of over 3,000 women with a personal history of breast cancer, researchers found that surveillance breast MRI facilitated a 59 percent lower risk in advanced presentations of second breast cancers.
New Survey Explores Radiologist and Neurologist Comfort Level with AI Triage for Brain MRI
January 7th 2025Survey results revealed that 71 percent of clinicians preferred adjunctive AI in facilitating triage of brain MRI scans and 58 percent were comfortable utilizing AI triage without input from radiologists.